Service Advantage
- High throughput and fast analysis speed
- Can undergo intracellular cross-linking
- No need for special chemical labeling of proteins
- Cross-linking agents can covalently connect two or more interacting proteins and retain short-lived/weak interactions.
Description of Service
- Chemical cross-linking coupled with mass spectrometry（XL-MS）is an important technique for examining protein-protein interactions (PPIs).
- It uses cross-linking agents to Chemically cross-link proteins and their complexes that interact within a certain distance.
- Then Mass spectrometry analyzes cross-linked peptides, depicts protein interaction networks, and identifies their sites of action.
- XL-MS can also be used in conjunction with other techniques, such as cryo-electron microscopy (cryo-EM) and X-ray crystal diffraction, for research on biological structures.
Service Process
- Customers can send cross-linked samples or contact us to develop a cross-linking plan and send the samples.
- We will complete the entire process of enzyme digestion, peptide enrichment, mass spectrometry detection, data analysis, and deliver the experimental report.
Why Choose Our Cutting-Edge Genomics Solutions?
Our cutting-edge genomics solutions, advanced laboratory instruments, and high-quality laboratory reagents and consumables are designed to provide all-round support for your scientific research and innovation. From DNA sequencing and molecular diagnostics to precision laboratory equipment, we provide reliable products that are widely used in academic, clinical and industrial fields. Our solutions are designed for modern scientific progress, helping laboratories improve efficiency and accuracy, and ensuring efficient advancement of scientific research and accurate results.