Skip to product information
Cryo-EM Technology Platform

Cryo-EM Technology Platform

$17,699.12

Cryo-electron microscopy (Cryo-EM) can rapidly determine protein structures in near-physiological states and is playing an increasingly important role in drug discovery. It is especially suitable for targets that are challenging for traditional X-ray crystallography or NMR, such as protein complexes, membrane proteins, or PROTAC/molecular glue ternary complexes.

Service Advantage

  • The three-dimensional structure of macromolecular proteins can be obtained without crystallization and with a very small amount of sample required.
  • The amorphous state ensures that electron beam detection will not cause interference to the sample imaging.
  • Using electron tomography requires lower sample requirements than single particle analysis.
  • Can resolve structures at atomic-level resolution (0.2-0.3 nm).

Description of Service

  • Cryo‐electron microscopy (cryo‐EM) is a structural biological method that is used to determine the 3D structures of biomacromolecules. 
  • Its purpose is to observe the structure of the sample in its original state as close as possible.
  • It is especially suitable for samples containing water and is an important characterization tool for studying biological samples. 
  • Using the solution of sample in-situ freezing--electron tomography--three-dimensional reconstruction, we can obtain the 3D structure diagram of macromolecular biological samples, which is a great tool for studying protein structure.
  • With the development of technology, the application scope of cryo-EM has been further expanded. In addition to common protein structure research, it can also be used to study special materials that are sensitive to electron beams and heat.

Service Process

  • Customers only need to send samples, and we will complete the sample preparation, sample imaging, three-dimensional reconstruction process, and issue an experimental result report.

Why Choose Our Cutting-Edge Genomics Solutions?

Our cutting-edge genomics solutions, advanced laboratory instruments, and high-quality laboratory reagents and consumables are designed to provide all-round support for your scientific research and innovation. From DNA sequencing and molecular diagnostics to precision laboratory equipment, we provide reliable products that are widely used in academic, clinical and industrial fields. Our solutions are designed for modern scientific progress, helping laboratories improve efficiency and accuracy, and ensuring efficient advancement of scientific research and accurate results.

You may also like